A data-driven Boolean model evolution in CD8+ T cell exhaustion

A data-driven Boolean model evolution in CD8+ T cell exhaustion
  • T cells play a key role in a variety of immune responses, including infection and cancer.
  • Upon stimulation, na├»ve CD8+ T cells proliferate and differentiate into a variety of memory and effector cell types.
  • T cell exhaustion (TCE) is the result of prolonged CD8+ T cell stimulation, which is caused by antigens that aren’t cleared.
Posted in Computer Modeling.

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